CONGRATULATIONS DR GOYAL FOR WINNING THE FIRST FRIDAY TEASER 🙂
Answer is E
Review of the question:
This patient’s clinical presentation and CT imaging are consistent with the diagnosis of idiopathic pulmonary fibrosis (IPF), which is manifested histologically as usual interstitial pneumonitis (UIP). On microscopic examination, UIP is characterized by a heterogeneous appearance on low magnification with normal appearing alveoli adjacent to severely fibrotic alveoli. The typical clinical presentation of IPF/UIP is slowly progressive exertional dyspnea with a nonproductive cough. Clinical examination reveals dry crackles and digital clubbing. A high-resolution CT scan of the chest can be diagnostic, in the typical clinical situation of an older individual and shows subpleural pulmonary fibrosis that is greatest at the lung bases.
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